Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN95623.1Putative lipid kinase; COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase. (300 aa)    
Predicted Functional Partners:
AEN95622.1
COG1925 Phosphotransferase system, HPr-related proteins.
       0.704
whiA
Hypothetical protein; Involved in cell division and chromosome segregation.
       0.693
AEN95620.1
glmZ(sRNA)-inactivating NTPase; Displays ATPase and GTPase activities.
       0.575
AEN95624.1
Fructose-1,6-bisphosphate aldolase, class II; COG0191 Fructose/tagatose bisphosphate aldolase.
     
 0.531
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
    
  0.515
murB
Hypothetical protein; Cell wall formation.
       0.485
AEN96705.1
COG1295 Predicted membrane protein; Belongs to the UPF0761 family.
 
    0.445
AEN95618.1
COG1362 Aspartyl aminopeptidase.
       0.427
AEN97041.1
COG0067 Glutamate synthase domain 1.
  
  
 0.407
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.