Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN95630.1Thymidylate synthase. (216 aa)    
Predicted Functional Partners:
AEN95629.1
Penicillin-binding protein 1A; COG5009 Membrane carboxypeptidase/penicillin-binding protein.
       0.573
AEN96108.1
Hypothetical protein; COG2384 Predicted SAM-dependent methyltransferase.
   
    0.485
AEN98048.1
COG0598 Mg2+ and Co2+ transporters.
  
    0.472
AEN95632.1
S1 RNA binding domain protein; COG2996 Uncharacterized protein conserved in bacteria; Belongs to the CvfB family.
       0.436
AEN95631.1
COG3884 Acyl-ACP thioesterase.
       0.433
AEN96311.1
RNA methylase NOL1/NOP2/sun family protein; COG0144 tRNA and rRNA cytosine-C5-methylases.
   
  
 0.409
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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