Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN95641.1Metallopeptidase M23 family protein; COG3883 Uncharacterized protein conserved in bacteria. (403 aa)    
Predicted Functional Partners:
AEN95640.1
Cell division transport system permease protein; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
 
  
 0.925
ftsE
Putative ATPase involved in cell division; Part of the ABC transporter FtsEX involved in cellular division.
 
   
 0.892
AEN95642.1
COG0793 Periplasmic protease; Belongs to the peptidase S41A family.
 
 
 
 0.709
AEN96517.1
Flagellar motor switch protein; COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation.
   
   0.633
AEN95629.1
Penicillin-binding protein 1A; COG5009 Membrane carboxypeptidase/penicillin-binding protein.
  
   
 0.585
AEN95638.1
Hypothetical protein; COG2508 Regulator of polyketide synthase expression.
       0.512
AEN95643.1
Hypothetical protein; COG5652 Predicted integral membrane protein.
       0.492
AEN97928.1
COG0744 Membrane carboxypeptidase (penicillin-binding protein).
  
   
 0.446
AEN97065.1
COG0681 Signal peptidase I; Belongs to the peptidase S26 family.
  
  
 0.440
AEN97514.1
Glycosyl transferase GT26 family protein; COG1922 Teichoic acid biosynthesis proteins; Belongs to the glycosyltransferase 26 family.
     0.418
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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