STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN95649.1COG4492 ACT domain-containing protein; Belongs to the UPF0735 family. (147 aa)    
Predicted Functional Partners:
AEN96742.1
Prephenate dehydratase; COG1605 Chorismate mutase.
  
 
 0.929
AEN96696.1
COG0287 Prephenate dehydrogenase.
     
 0.907
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
     
  0.900
AEN96425.1
COG0147 Anthranilate/para-aminobenzoate synthases component I.
     
  0.900
AEN96426.1
COG0512 Anthranilate/para-aminobenzoate synthases component II.
     
  0.900
AEN95650.1
COG0460 Homoserine dehydrogenase.
       0.761
AEN95651.1
Proposed homoserine kinase; COG3635 Predicted phosphoglycerate mutase, AP superfamily.
       0.642
prfB
Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
       0.534
AEN95646.1
COG4260 Putative virion core protein (lumpy skin disease virus).
       0.523
AEN95647.1
Hypothetical protein.
       0.483
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.