STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN95650.1COG0460 Homoserine dehydrogenase. (401 aa)    
Predicted Functional Partners:
AEN96831.1
COG0136 Aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
 0.985
AEN96715.1
COG0498 Threonine synthase.
 
 
 0.968
AEN97636.1
COG0527 Aspartokinases; Belongs to the aspartokinase family.
 
 0.968
AEN97353.1
COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.
  
 
 0.953
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
 
 0.951
metAA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
  
 
 0.950
AEN95893.1
COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase.
 
 
 0.902
AEN97331.1
COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.
  
 
 0.901
AEN96937.1
COG2873 O-acetylhomoserine sulfhydrylase.
 
 
 0.890
AEN97351.1
COG1045 Serine acetyltransferase.
  
  
 0.860
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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