STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN95709.1Cell surface protein; COG4870 Cysteine protease. (568 aa)    
Predicted Functional Partners:
AEN95708.1
Nucleic acid methylase; COG0116 Predicted N6-adenine-specific DNA methylase.
       0.817
AEN95711.1
COG0860 N-acetylmuramoyl-L-alanine amidase.
       0.750
AEN95712.1
Ribonuclease Ph; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
       0.747
AEN95710.1
N-acetylmuramoyl-L-alanine amidase.
       0.737
AEN95713.1
Phosphodiesterase, MJ0936 family protein; COG0622 Predicted phosphoesterase.
       0.727
AEN95889.1
COG4826 Serine protease inhibitor; Belongs to the serpin family.
  
 
 0.701
AEN95707.1
Rhodanese domain protein; COG0607 Rhodanese-related sulfurtransferase.
       0.611
AEN95945.1
Hypothetical protein.
  
    0.608
AEN96375.1
Hypothetical protein.
  
     0.597
AEN95689.1
Hypothetical protein.
  
     0.583
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.