Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN95733.1COG0411 ABC-type branched-chain amino acid transport systems, ATPase component. (252 aa)    
Predicted Functional Partners:
AEN95731.1
Inner-membrane translocator; COG0559 Branched-chain amino acid ABC-type transport system, permease components; Belongs to the binding-protein-dependent transport system permease family.
 
 
 0.999
AEN95732.1
Inner-membrane translocator; COG4177 ABC-type branched-chain amino acid transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.
 
 0.999
AEN95730.1
Extracellular ligand-binding receptor; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.
 
 
 0.998
AEN95734.1
ABC transporter related protein; COG0410 ABC-type branched-chain amino acid transport systems, ATPase component.
 
 
0.997
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.637
AEN95735.1
Hypothetical protein; COG1102 Cytidylate kinase.
       0.624
AEN97772.1
COG1131 ABC-type multidrug transport system, ATPase component.
     
0.498
AEN95736.1
pepF/M3 family oligoendopeptidase; COG1164 Oligoendopeptidase F.
       0.420
AEN95737.1
Hypothetical protein; COG1453 Predicted oxidoreductases of the aldo/keto reductase family.
       0.406
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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