Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
AEN95745.1Cupin 2 conserved barrel domain protein; COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain. (136 aa)    
Predicted Functional Partners:
kduI
5-keto-4-deoxyuronate isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.
 
  
  0.961
AEN95744.1
TRAP dicarboxylate transporter, DctP subunit; COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component.
       0.748
AEN95742.1
Integral membrane sensor signal transduction histidine kinase; COG2972 Predicted signal transduction protein with a C-terminal ATPase domain.
       0.741
AEN95743.1
COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain.
       0.741
AEN95739.1
Tripartite ATP-independent periplasmic transporter DctQ component; COG3090 TRAP-type C4-dicarboxylate transport system, small permease component.
 
     0.570
AEN95741.1
Hypothetical protein.
       0.533
AEN96572.1
Glucosyl hydrolase family protein; COG4225 Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins.
 
     0.531
AEN95740.1
TRAP dicarboxylate transporter, DctM subunit; COG1593 TRAP-type C4-dicarboxylate transport system, large permease component.
       0.490
AEN95221.1
Glycoside hydrolase family protein; COG5434 Endopolygalacturonase; Belongs to the glycosyl hydrolase 28 family.
 
     0.417
AEN96748.1
Glycoside hydrolase family 28; COG5434 Endopolygalacturonase; Belongs to the glycosyl hydrolase 28 family.
 
     0.405
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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