| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEN95540.1 | clpP | RHOM_02090 | RHOM_03290 | ICESt1 ORFD ATP/GTP-binding protein; COG0542 ATPases with chaperone activity, ATP-binding subunit. | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.913 |
| AEN95540.1 | groL | RHOM_02090 | RHOM_09330 | ICESt1 ORFD ATP/GTP-binding protein; COG0542 ATPases with chaperone activity, ATP-binding subunit. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.597 |
| AEN95540.1 | groS | RHOM_02090 | RHOM_09335 | ICESt1 ORFD ATP/GTP-binding protein; COG0542 ATPases with chaperone activity, ATP-binding subunit. | Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.555 |
| AEN95540.1 | lon | RHOM_02090 | RHOM_03300 | ICESt1 ORFD ATP/GTP-binding protein; COG0542 ATPases with chaperone activity, ATP-binding subunit. | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.651 |
| AEN96076.1 | clpP | RHOM_04780 | RHOM_03290 | COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.920 |
| AEN96076.1 | groL | RHOM_04780 | RHOM_09330 | COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.541 |
| AEN96076.1 | groS | RHOM_04780 | RHOM_09335 | COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.555 |
| AEN96076.1 | lon | RHOM_04780 | RHOM_03300 | COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.651 |
| clpB | clpP | RHOM_03585 | RHOM_03290 | Heat shock protein ClpB-like protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.912 |
| clpB | clpX | RHOM_03585 | RHOM_03825 | Heat shock protein ClpB-like protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | COG1219 ATP-dependent protease Clp, ATPase subunit. | 0.642 |
| clpB | clpX-2 | RHOM_03585 | RHOM_03295 | Heat shock protein ClpB-like protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | ATP-dependent protease ATP-binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.642 |
| clpB | groL | RHOM_03585 | RHOM_09330 | Heat shock protein ClpB-like protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.757 |
| clpB | groS | RHOM_03585 | RHOM_09335 | Heat shock protein ClpB-like protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.732 |
| clpB | lon | RHOM_03585 | RHOM_03300 | Heat shock protein ClpB-like protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.651 |
| clpP | AEN95540.1 | RHOM_03290 | RHOM_02090 | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ICESt1 ORFD ATP/GTP-binding protein; COG0542 ATPases with chaperone activity, ATP-binding subunit. | 0.913 |
| clpP | AEN96076.1 | RHOM_03290 | RHOM_04780 | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | 0.920 |
| clpP | clpB | RHOM_03290 | RHOM_03585 | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Heat shock protein ClpB-like protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.912 |
| clpP | clpX | RHOM_03290 | RHOM_03825 | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | COG1219 ATP-dependent protease Clp, ATPase subunit. | 0.985 |
| clpP | clpX-2 | RHOM_03290 | RHOM_03295 | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATP-dependent protease ATP-binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.994 |
| clpP | engB | RHOM_03290 | RHOM_03305 | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | GTPase EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 0.736 |
