Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN95826.1Heavy-metal transporting P-type ATPase; COG2217 Cation transport ATPase. (888 aa)    
Predicted Functional Partners:
AEN96793.1
Hypothetical protein; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
   
 0.963
AEN95825.1
COG1937 Uncharacterized protein conserved in bacteria.
 
  
 0.916
AEN97229.1
COG2608 Copper chaperone.
  
 
 0.857
AEN97444.1
Peptidyl-prolyl cis-trans isomerase cyclophilin-type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
 
   0.817
AEN97146.1
Hypothetical protein; COG2217 Cation transport ATPase.
 
 
0.755
AEN95817.1
COG0640 Predicted transcriptional regulators.
 
  
 0.751
AEN95819.1
Heavy metal translocating P-type ATPase; COG2217 Cation transport ATPase.
 
 
0.743
AEN97501.1
Hypothetical protein; COG3682 Predicted transcriptional regulator.
  
  
 0.726
AEN98166.1
Penicillinase repressor; COG3682 Predicted transcriptional regulator.
  
  
 0.726
AEN95828.1
COG0642 Signal transduction histidine kinase.
  
  
 0.697
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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