STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN95827.1HD-GYP domain-containing protein; COG2206 HD-GYP domain. (481 aa)    
Predicted Functional Partners:
AEN95559.1
Signaling protein; COG2199 FOG: GGDEF domain.
 
 0.940
AEN95828.1
COG0642 Signal transduction histidine kinase.
 
 
 0.919
AEN98437.1
COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain.
 
 
 0.876
AEN96517.1
Flagellar motor switch protein; COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation.
 
 
 0.830
AEN96086.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); COG2199 FOG: GGDEF domain.
 
 
 0.807
AEN96391.1
Diguanylate cyclase/phosphodiesterase; COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain.
 
 
0.806
AEN95402.1
Hypothetical protein; COG2199 FOG: GGDEF domain.
 
 0.778
AEN95849.1
Signaling protein; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.
 
 
 0.770
AEN95792.1
Two-component system, PleD related family, response regulator; COG2199 FOG: GGDEF domain.
 
 
 0.768
AEN95379.1
PAS/PAC sensor hybrid histidine kinase; COG0784 FOG: CheY-like receiver.
 
 
 0.764
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.