Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN95877.1Hypothetical protein; COG0546 Predicted phosphatases. (284 aa)    
Predicted Functional Partners:
AEN95878.1
Glycoside hydrolase family 3 protein; COG1472 Beta-glucosidase-related glycosidases.
   
 0.949
AEN95876.1
D-mannonate oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
    0.688
AEN97244.1
Sugar transporter; COG2211 Na+/melibiose symporter and related transporters.
 
    0.662
hisI
COG0107 Imidazoleglycerol-phosphate synthase; In the C-terminal section; belongs to the PRA-PH family.
  
  
 0.601
uxuA-2
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
       0.529
AEN97242.1
Xylose isomerase domain-containing protein TIM barrel; COG1082 Sugar phosphate isomerases/epimerases.
  
     0.496
AEN98346.1
Radical SAM domain-containing protein; COG0535 Predicted Fe-S oxidoreductases.
  
    0.490
AEN97243.1
Beta-glucuronidase; COG3250 Beta-galactosidase/beta-glucuronidase; Belongs to the glycosyl hydrolase 2 family.
 
     0.482
AEN96087.1
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.
     
 0.455
AEN97246.1
AraC family transcriptional regulator; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes.
  
    0.447
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.