Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN95948.1Integral membrane sensor signal transduction histidine kinase; COG2972 Predicted signal transduction protein with a C-terminal ATPase domain. (549 aa)    
Predicted Functional Partners:
AEN95947.1
COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain.
 
 
 0.968
AEN96615.1
Two component system response regulator; COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain.
 
 
 0.884
AEN97412.1
Two component AraC family transcriptional regulator; COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain.
 
 
 0.874
AEN95831.1
COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain.
 
 
 0.864
AEN95902.1
COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain.
 
 
 0.858
AEN96272.1
Hypothetical protein; COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain.
 
 
 0.781
AEN98379.1
COG3279 Response regulator of the LytR/AlgR family.
 
  
 0.734
AEN97388.1
Two-component system, response regulator YesN; COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain.
 
 
  0.732
AEN98046.1
Two-component system, response regulator YesN; COG2207 AraC-type DNA-binding domain-containing proteins.
 
 
  0.716
AEN95949.1
Extracellular solute-binding protein family 1; COG1653 ABC-type sugar transport system, periplasmic component.
 
     0.583
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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