Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN95961.1Hypothetical protein. (88 aa)    
Predicted Functional Partners:
AEN95962.1
COG1896 Predicted hydrolases of HD superfamily.
       0.775
AEN95960.1
VanZ family protein; COG4767 Glycopeptide antibiotics resistance protein.
       0.688
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
       0.667
AEN95963.1
Hypothetical protein; COG2309 Leucyl aminopeptidase (aminopeptidase T).
       0.572
AEN95957.1
Prevent-host-death family protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
       0.416
AEN95958.1
COG4115 Uncharacterized protein conserved in bacteria.
       0.416
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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