STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEN95976.1Glycosyltransferase Family 35 candidate a-glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (825 aa)    
Predicted Functional Partners:
glgB
1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
 
 0.990
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
 
 
 0.984
AEN97739.1
COG0448 ADP-glucose pyrophosphorylase; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
 
 
 0.983
AEN96444.1
COG1640 4-alpha-glucanotransferase.
 
 
 0.979
AEN96493.1
Glycogen operon protein GlgX; COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases; Belongs to the glycosyl hydrolase 13 family.
 
 
 0.954
AEN98062.1
Glycogen debranching enzyme GlgX; COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases; Belongs to the glycosyl hydrolase 13 family.
 
 
 0.954
AEN95170.1
Neopullulanase; COG0366 Glycosidases.
  
 0.925
AEN95829.1
Alpha amylase catalytic region; COG0366 Glycosidases; Belongs to the glycosyl hydrolase 13 family.
  
 0.925
AEN97487.1
Cyclomaltodextrinase; COG0366 Glycosidases.
  
 0.925
AEN97662.1
Alpha-amylase; COG0366 Glycosidases.
  
 0.924
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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