STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN96021.1COG1453 Predicted oxidoreductases of the aldo/keto reductase family. (394 aa)    
Predicted Functional Partners:
nadE
NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
       0.781
hslO
Chaperonin, 33 kDa; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
       0.773
AEN96018.1
Hypothetical protein.
       0.642
AEN96017.1
Methyltransferase type 12; COG0500 SAM-dependent methyltransferases.
       0.613
AEN96025.1
PP-loop domain protein; COG1606 ATP-utilizing enzymes of the PP-loop superfamily.
 
    0.539
AEN96022.1
COG4720 Predicted membrane protein.
       0.538
AEN96016.1
Hypothetical protein.
       0.426
AEN96097.1
NADPH-dependent FMN reductase; COG0655 Multimeric flavodoxin WrbA.
 
     0.413
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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