Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AEN96044.1Hypothetical protein. (194 aa)    
Predicted Functional Partners:
AEN96045.1
Transcriptional regulator, BadM/Rrf2 family protein; COG1959 Predicted transcriptional regulator.
     
 0.783
AEN96043.1
COG0822 NifU homolog involved in Fe-S cluster formation.
       0.773
AEN96046.1
Transcriptional regulator, BadM/Rrf2 family protein; COG1959 Predicted transcriptional regulator.
     
 0.763
iscS
Cysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
   
   0.702
AEN96991.1
NADPH-dependent glutamate synthase GltA2; COG1145 Ferredoxin.
  
  
 0.636
AEN98326.1
COG1145 Ferredoxin.
  
  
 0.596
AEN97938.1
COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.
  
  
 0.542
birA
Putative transcriptional repressor of the biotin operon birA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
    0.532
AEN96254.1
COG0778 Nitroreductase.
  
  
 0.494
tadA
Cytidine and deoxycytidylate deaminase family protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
   
  
 0.494
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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