Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AEN96079.1COG1342 Predicted DNA-binding proteins; Belongs to the UPF0251 family. (262 aa)    
Predicted Functional Partners:
AEN95683.1
Mrp family protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
 
  
 0.740
AEN96991.1
NADPH-dependent glutamate synthase GltA2; COG1145 Ferredoxin.
 
  
 0.739
AEN96080.1
Hypothetical protein.
       0.705
AEN96081.1
Hypothetical protein.
       0.608
AEN96087.1
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.
     
 0.582
AEN97479.1
Hypothetical protein.
      0.499
AEN97938.1
COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.
 
     0.497
AEN97378.1
4Fe-4S ferredoxin, iron-sulfur binding protein; COG1145 Ferredoxin.
  
  
 0.467
AEN95310.1
Hypothetical protein.
  
     0.449
AEN95811.1
COG1918 Fe2+ transport system protein A.
 
   
 0.439
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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