Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
AEN96083.1NLP/P60 family protein; COG3103 SH3 domain protein. (451 aa)    
Predicted Functional Partners:
AEN97728.1
NLP/P60 protein; COG3883 Uncharacterized protein conserved in bacteria.
 
  
0.577
AEN96084.1
ROK family protein; COG1940 Transcriptional regulator/sugar kinase.
       0.542
AEN95640.1
Cell division transport system permease protein; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
 
 
 
 0.465
AEN96887.1
COG3103 SH3 domain protein.
 
    0.455
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
 
   
 0.427
AEN96082.1
COG3773 Cell wall hydrolyses involved in spore germination.
  
    0.422
nnrE
YjeF-like protein/carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the r [...]
  
    0.407
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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