Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
AEN96094.1Organic radical activating enzyme; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (172 aa)    
Predicted Functional Partners:
AEN96093.1
COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase.
 
 
 0.995
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.621
AEN96095.1
Hypothetical protein.
       0.551
AEN97044.1
Putative phosphatase, HAD family protein; COG0546 Predicted phosphatases.
 
      0.491
AEN96208.1
Hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
  
  
 0.463
AEN96148.1
COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain.
 
   
 0.458
AEN96092.1
COG1846 Transcriptional regulators.
 
     0.447
rlmH
rRNA large subunit methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
   
    0.440
AEN96355.1
Putative R-2-hydroxyglutaryl-CoA dehydratase subunit/R-2-hydroxyglutaryl-CoA dehydratase activase; COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain).
       0.420
AEN96096.1
Flagellin lysine-N-methylase.
       0.400
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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