| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEN96148.1 | AEN96160.1 | RHOM_05145 | RHOM_05205 | COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain. | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.996 |
| AEN96148.1 | AEN97093.1 | RHOM_05145 | RHOM_09910 | COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain. | 5-aminoimidazole-4-carboxamide ribonucleotide transformylase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). | 0.996 |
| AEN96148.1 | guaA | RHOM_05145 | RHOM_13030 | COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.989 |
| AEN96148.1 | pheT | RHOM_05145 | RHOM_07950 | COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain. | phenylalanyl-tRNA synthetase, beta subunit; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.972 |
| AEN96148.1 | purC | RHOM_05145 | RHOM_05190 | COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain. | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | 0.996 |
| AEN96148.1 | purD | RHOM_05145 | RHOM_04225 | COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain. | COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | 0.999 |
| AEN96148.1 | purE | RHOM_05145 | RHOM_04210 | COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain. | Phosphoribosylaminoimidazole carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.999 |
| AEN96148.1 | purF | RHOM_05145 | RHOM_05195 | COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.998 |
| AEN96148.1 | purM | RHOM_05145 | RHOM_04215 | COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain. | Phosphoribosylformylglycinamidine cyclo-ligase; COG0150 Phosphoribosylaminoimidazole (AIR) synthetase. | 0.999 |
| AEN96148.1 | purN | RHOM_05145 | RHOM_04220 | COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.999 |
| AEN96160.1 | AEN96148.1 | RHOM_05205 | RHOM_05145 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain. | 0.996 |
| AEN96160.1 | AEN97093.1 | RHOM_05205 | RHOM_09910 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 5-aminoimidazole-4-carboxamide ribonucleotide transformylase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). | 0.996 |
| AEN96160.1 | guaA | RHOM_05205 | RHOM_13030 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.908 |
| AEN96160.1 | pheT | RHOM_05205 | RHOM_07950 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | phenylalanyl-tRNA synthetase, beta subunit; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.655 |
| AEN96160.1 | purC | RHOM_05205 | RHOM_05190 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. | 0.999 |
| AEN96160.1 | purD | RHOM_05205 | RHOM_04225 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | 0.989 |
| AEN96160.1 | purE | RHOM_05205 | RHOM_04210 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazole carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.995 |
| AEN96160.1 | purF | RHOM_05205 | RHOM_05195 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.998 |
| AEN96160.1 | purM | RHOM_05205 | RHOM_04215 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine cyclo-ligase; COG0150 Phosphoribosylaminoimidazole (AIR) synthetase. | 0.992 |
| AEN96160.1 | purN | RHOM_05205 | RHOM_04220 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.945 |