AEN96185.1 protein (Roseburia hominis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

AEN96185.1

GTP-binding protein TypA; COG1217 Predicted membrane GTPase involved in stress response. (612 aa)

Predicted Functional Partners:

guaA

0.798

rpsI

0.634

ychF

0.612

AEN97041.1

0.611

rpmI

0.608

polA

0.607

tsf

0.599

rplA

0.594

infC

0.558

rimP

0.546

Your Current Organism:

Roseburia hominis

NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AEN96185.1	AEN97041.1	RHOM_05330	RHOM_09650	GTP-binding protein TypA; COG1217 Predicted membrane GTPase involved in stress response.	COG0067 Glutamate synthase domain 1.	0.611
AEN96185.1	guaA	RHOM_05330	RHOM_13030	GTP-binding protein TypA; COG1217 Predicted membrane GTPase involved in stress response.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.798
AEN96185.1	infC	RHOM_05330	RHOM_08105	GTP-binding protein TypA; COG1217 Predicted membrane GTPase involved in stress response.	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	0.558
AEN96185.1	polA	RHOM_05330	RHOM_09955	GTP-binding protein TypA; COG1217 Predicted membrane GTPase involved in stress response.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.607
AEN96185.1	rimP	RHOM_05330	RHOM_08515	GTP-binding protein TypA; COG1217 Predicted membrane GTPase involved in stress response.	Ribosome maturation protein RimP; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.	0.546
AEN96185.1	rplA	RHOM_05330	RHOM_00955	GTP-binding protein TypA; COG1217 Predicted membrane GTPase involved in stress response.	50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.594
AEN96185.1	rpmI	RHOM_05330	RHOM_08100	GTP-binding protein TypA; COG1217 Predicted membrane GTPase involved in stress response.	COG0291 Ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.	0.608
AEN96185.1	rpsI	RHOM_05330	RHOM_01475	GTP-binding protein TypA; COG1217 Predicted membrane GTPase involved in stress response.	COG0103 Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.634
AEN96185.1	tsf	RHOM_05330	RHOM_07120	GTP-binding protein TypA; COG1217 Predicted membrane GTPase involved in stress response.	Translation elongation factor Ts Tsf; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.	0.599
AEN96185.1	ychF	RHOM_05330	RHOM_05085	GTP-binding protein TypA; COG1217 Predicted membrane GTPase involved in stress response.	GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.	0.612
AEN97041.1	AEN96185.1	RHOM_09650	RHOM_05330	COG0067 Glutamate synthase domain 1.	GTP-binding protein TypA; COG1217 Predicted membrane GTPase involved in stress response.	0.611
AEN97041.1	guaA	RHOM_09650	RHOM_13030	COG0067 Glutamate synthase domain 1.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.769
AEN97041.1	polA	RHOM_09650	RHOM_09955	COG0067 Glutamate synthase domain 1.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.468
AEN97041.1	tsf	RHOM_09650	RHOM_07120	COG0067 Glutamate synthase domain 1.	Translation elongation factor Ts Tsf; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.	0.473
AEN97041.1	ychF	RHOM_09650	RHOM_05085	COG0067 Glutamate synthase domain 1.	GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.	0.476
guaA	AEN96185.1	RHOM_13030	RHOM_05330	GMP synthase; Catalyzes the synthesis of GMP from XMP.	GTP-binding protein TypA; COG1217 Predicted membrane GTPase involved in stress response.	0.798
guaA	AEN97041.1	RHOM_13030	RHOM_09650	GMP synthase; Catalyzes the synthesis of GMP from XMP.	COG0067 Glutamate synthase domain 1.	0.769
guaA	infC	RHOM_13030	RHOM_08105	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	0.512
guaA	polA	RHOM_13030	RHOM_09955	GMP synthase; Catalyzes the synthesis of GMP from XMP.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.776
guaA	rplA	RHOM_13030	RHOM_00955	GMP synthase; Catalyzes the synthesis of GMP from XMP.	50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.940

page 1 of 5

Server load: low (22%) [HD]

Permalink

Network

Neighborhood

Experiments

Co-occurrence

Databases

Co-expression

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About