Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
speESpermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (286 aa)    
Predicted Functional Partners:
AEN96193.1
Orn/Lys/Arg decarboxylase major region; COG1982 Arginine/lysine/ornithine decarboxylases.
  
 0.964
AEN96198.1
Beta-ureidopropionase; COG0388 Predicted amidohydrolase.
  
 
 0.950
AEN96452.1
COG0402 Cytosine deaminase and related metal-dependent hydrolases.
   
 0.907
AEN97058.1
Hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family.
    
  0.901
AEN96119.1
MTA/SAH nucleosidase; COG0775 Nucleoside phosphorylase.
    
  0.900
AEN96516.1
COG1868 Flagellar motor switch protein.
    
   0.775
AEN96196.1
COG0019 Diaminopimelate decarboxylase.
  
 
 0.709
AEN96195.1
COG1748 Saccharopine dehydrogenase and related proteins.
     
 0.657
aguA
Hypothetical protein; COG2957 Peptidylarginine deiminase and related enzymes.
     
 0.623
mtnA
Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
 
  
 0.578
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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