STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN96196.1COG0019 Diaminopimelate decarboxylase. (398 aa)    
Predicted Functional Partners:
AEN96195.1
COG1748 Saccharopine dehydrogenase and related proteins.
 
 
 0.994
aguA
Hypothetical protein; COG2957 Peptidylarginine deiminase and related enzymes.
     
 0.785
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
  
 
 0.709
AEN96198.1
Beta-ureidopropionase; COG0388 Predicted amidohydrolase.
 
   
 0.703
AEN96193.1
Orn/Lys/Arg decarboxylase major region; COG1982 Arginine/lysine/ornithine decarboxylases.
 
   
 0.647
hisI
COG0107 Imidazoleglycerol-phosphate synthase; In the C-terminal section; belongs to the PRA-PH family.
  
  
 0.628
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.570
AEN96742.1
Prephenate dehydratase; COG1605 Chorismate mutase.
     
 0.523
AEN98472.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.441
ribBA
GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
  
 0.417
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.