Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN96198.1Beta-ureidopropionase; COG0388 Predicted amidohydrolase. (292 aa)    
Predicted Functional Partners:
aguA
Hypothetical protein; COG2957 Peptidylarginine deiminase and related enzymes.
 
 0.998
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
  
 
 0.950
AEN96196.1
COG0019 Diaminopimelate decarboxylase.
 
   
 0.703
AEN96195.1
COG1748 Saccharopine dehydrogenase and related proteins.
  
  
 0.550
AEN96199.1
COG1846 Transcriptional regulators.
  
    0.549
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.520
AEN97041.1
COG0067 Glutamate synthase domain 1.
     
 0.516
birA
Putative transcriptional repressor of the biotin operon birA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.422
pstB
Phosphate transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
   
  
 0.415
AEN96742.1
Prephenate dehydratase; COG1605 Chorismate mutase.
  
  
 0.409
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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