Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN96211.1Hypothetical protein; COG1925 Phosphotransferase system, HPr-related proteins. (76 aa)    
Predicted Functional Partners:
AEN98306.1
PTS system, fructose-specific, IIABC component; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).
  
  
 0.775
AEN95638.1
Hypothetical protein; COG2508 Regulator of polyketide synthase expression.
  
     0.762
AEN97048.1
CdaR family transcriptional regulator; COG2508 Regulator of polyketide synthase expression.
  
     0.757
AEN96296.1
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
  
 
 0.726
AEN97461.1
Hypothetical protein.
  
     0.607
AEN98244.1
Hypothetical protein.
  
     0.597
AEN97590.1
Hypothetical protein.
  
     0.588
AEN96212.1
MiaB-like tRNA modifying enzyme; COG0621 2-methylthioadenine synthetase.
       0.576
AEN98272.1
Hypothetical protein; COG4862 Negative regulator of genetic competence, sporulation and motility.
  
     0.550
AEN96947.1
Cell division protein FtsQ; Essential cell division protein.
  
     0.527
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.