Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN96219.1Peptidase U32; COG0826 Collagenase and related proteases. (407 aa)    
Predicted Functional Partners:
AEN96218.1
COG4122 Predicted O-methyltransferase.
 
  
 0.923
AEN96220.1
COG2706 3-carboxymuconate cyclase.
       0.757
AEN96217.1
Hypothetical protein; COG1559 Predicted periplasmic solute-binding protein.
  
    0.678
rnj
Putative hydrolase of the metallo-beta-lactamase superfamily protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
       0.670
AEN96213.1
COG4472 Uncharacterized protein conserved in bacteria; Belongs to the UPF0297 family.
 
     0.648
AEN96214.1
Hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.
       0.621
AEN96215.1
Hypothetical protein.
       0.620
AEN95296.1
O-methyltransferase; COG1086 Predicted nucleoside-diphosphate sugar epimerases.
  
  
 0.501
AEN96212.1
MiaB-like tRNA modifying enzyme; COG0621 2-methylthioadenine synthetase.
  
  
 0.485
AEN98072.1
UBA/THIF-type NAD/FAD binding protein; COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1.
  
     0.457
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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