Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN96244.1Hypothetical protein. (328 aa)    
Predicted Functional Partners:
AEN96243.1
COG0642 Signal transduction histidine kinase.
 
    0.942
AEN96245.1
COG0658 Predicted membrane metal-binding protein.
 
     0.863
AEN96241.1
COG1555 DNA uptake protein and related DNA-binding proteins.
  
    0.804
AEN96242.1
COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
   
 0.783
AEN96641.1
Hypothetical protein.
 
     0.768
AEN97590.1
Hypothetical protein.
  
     0.766
AEN96947.1
Cell division protein FtsQ; Essential cell division protein.
  
     0.759
AEN95799.1
Hypothetical protein; COG0457 FOG: TPR repeat.
  
     0.757
AEN97461.1
Hypothetical protein.
  
     0.756
AEN96651.1
COG2891 Cell shape-determining protein.
  
     0.753
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
Server load: medium (54%) [HD]