Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN96297.1COG1925 Phosphotransferase system, HPr-related proteins. (85 aa)    
Predicted Functional Partners:
AEN96296.1
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.998
AEN98306.1
PTS system, fructose-specific, IIABC component; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).
 
 
 0.979
AEN96697.1
PTS system, N-acetylglucosamine-specific IIBC component; COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.
 
 
 0.949
AEN97747.1
COG1925 Phosphotransferase system, HPr-related proteins.
  
  
 
0.916
AEN97586.1
COG1925 Phosphotransferase system, HPr-related proteins.
  
  
 
0.913
AEN96145.1
Hypothetical protein; COG1925 Phosphotransferase system, HPr-related proteins.
     
  0.900
AEN96294.1
Phosphotransferase system PTS lactose/cellobiose-specific transporter subunit IIA; COG1447 Phosphotransferase system cellobiose-specific component IIA.
   
 0.874
AEN96295.1
COG1440 Phosphotransferase system cellobiose-specific component IIB.
    
  0.847
AEN95809.1
COG1447 Phosphotransferase system cellobiose-specific component IIA.
   
 0.719
AEN95807.1
COG1440 Phosphotransferase system cellobiose-specific component IIB.
    
  0.659
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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