Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN96312.1Hypothetical protein. (201 aa)    
Predicted Functional Partners:
AEN96912.1
precorrin-6Y C(5,15)-methyltransferase; COG2099 Precorrin-6x reductase.
     
 0.679
AEN96311.1
RNA methylase NOL1/NOP2/sun family protein; COG0144 tRNA and rRNA cytosine-C5-methylases.
  
    0.617
AEN96906.1
Sirohydrochlorin cobaltochelatase; COG4822 Cobalamin biosynthesis protein CbiK, Co2+ chelatase.
     
 0.610
AEN96917.1
precorrin-8X methylmutase CbiC/CobH; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase.
     
 0.601
AEN97353.1
COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.
     
 0.590
AEN96313.1
COG0642 Signal transduction histidine kinase.
       0.519
hisI
COG0107 Imidazoleglycerol-phosphate synthase; In the C-terminal section; belongs to the PRA-PH family.
      
 0.447
AEN96310.1
COG4624 Iron only hydrogenase large subunit, C-terminal domain.
       0.425
cobS
Cobalamin 5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
  
  
 0.412
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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