Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AEN96316.1Hypothetical protein. (322 aa)    
Predicted Functional Partners:
AEN96315.1
ECF subfamily RNA polymerase sigma-24 factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.
 
   0.921
AEN96317.1
Hypothetical protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
       0.655
AEN96314.1
COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain.
  
    0.578
AEN95656.1
Putative sporulation protein YtaF; Probably functions as a manganese efflux pump.
 
     0.516
AEN97343.1
COG0642 Signal transduction histidine kinase.
  
     0.446
AEN96318.1
Hypothetical protein.
       0.432
AEN97794.1
Hypothetical protein.
 
     0.418
AEN96826.1
Hypothetical protein.
 
   0.401
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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