Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN96331.1AraC family transcriptional regulator; COG2207 AraC-type DNA-binding domain-containing proteins. (330 aa)    
Predicted Functional Partners:
AEN96332.1
Rhamnulokinase; COG1070 Sugar (pentulose and hexulose) kinases.
 
  
 0.840
AEN97511.1
Transcriptional regulator, AraC family protein; COG2207 AraC-type DNA-binding domain-containing proteins.
  
   0.770
rhaA
COG4806 L-rhamnose isomerase; Belongs to the rhamnose isomerase family.
 
  
 0.765
AEN97246.1
AraC family transcriptional regulator; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes.
 
   0.751
AEN97300.1
L-rhamnose operon transcriptional activator; COG2207 AraC-type DNA-binding domain-containing proteins.
  
   0.725
AEN97402.1
AraC family transcriptional regulator; COG2207 AraC-type DNA-binding domain-containing proteins.
  
   0.721
AEN95368.1
AraC family transcriptional regulator; COG2207 AraC-type DNA-binding domain-containing proteins.
 
   0.705
rhaD
Rhamnulose-1-phosphate aldolase; Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
 
   
 0.691
AEN95940.1
AraC family transcriptional regulator; COG2207 AraC-type DNA-binding domain-containing proteins.
 
 
0.676
AEN97935.1
AraC family transcription regulator; COG2207 AraC-type DNA-binding domain-containing proteins.
  
   0.589
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
Server load: low (40%) [HD]