Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rhaACOG4806 L-rhamnose isomerase; Belongs to the rhamnose isomerase family. (416 aa)    
Predicted Functional Partners:
AEN96332.1
Rhamnulokinase; COG1070 Sugar (pentulose and hexulose) kinases.
 
 
 0.997
rhaD
Rhamnulose-1-phosphate aldolase; Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
 
  
 0.975
AEN96331.1
AraC family transcriptional regulator; COG2207 AraC-type DNA-binding domain-containing proteins.
 
  
 0.765
araA
L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose.
     
 0.724
pfkA-2
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
      
 0.694
galK
Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.
      
 0.690
pgi
COG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family.
      
 0.690
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
   
 0.684
uxaC
COG1904 Glucuronate isomerase.
      
 0.684
xylB
Xylulokinase; COG1070 Sugar (pentulose and hexulose) kinases.
  
  
 0.680
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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