STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEN96335.1AddB; ATP-dependent DNA helicase. (1188 aa)    
Predicted Functional Partners:
addA
DNA helicase II; ATP-dependent DNA helicase.
 
 
 0.999
AEN96337.1
Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
       0.648
sbcD
Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
 
  
 0.564
AEN96338.1
Hypothetical protein.
       0.548
AEN96108.1
Hypothetical protein; COG2384 Predicted SAM-dependent methyltransferase.
 
     0.547
AEN97656.1
SMC domain protein; COG0419 ATPase involved in DNA repair.
 
  
 0.485
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
 
   
 0.474
recU
Holliday junction-specific endonuclease; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family.
  
   
 0.462
AEN96662.1
Stage V sporulation protein B, putative; COG2244 Membrane protein involved in the export of O-antigen and teichoic acid.
  
     0.441
AEN95911.1
single-stranded-DNA-specific exonuclease RecJ; COG0608 Single-stranded DNA-specific exonuclease.
     
 0.419
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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