Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hcpHybrid cluster protein; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O. (531 aa)    
Predicted Functional Partners:
AEN97913.1
COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.909
AEN96176.1
COG0174 Glutamine synthetase.
     
 0.906
hcp-2
Hybrid cluster protein; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
  
  
 
0.904
AEN95625.1
COG3968 Uncharacterized protein related to glutamine synthetase.
     
  0.900
AEN96087.1
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.
 
   
 0.635
AEN96348.1
COG0726 Predicted xylanase/chitin deacetylase.
       0.524
AEN98112.1
Hypothetical protein.
     
 0.448
AEN96991.1
NADPH-dependent glutamate synthase GltA2; COG1145 Ferredoxin.
     
 0.431
AEN96347.1
Hypothetical protein.
       0.406
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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