Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AEN96400.1COG1309 Transcriptional regulator. (190 aa)    
Predicted Functional Partners:
AEN96402.1
Hypothetical protein.
 
     0.867
AEN96403.1
Sugar transporter; COG2211 Na+/melibiose symporter and related transporters.
 
     0.830
AEN96401.1
COG3250 Beta-galactosidase/beta-glucuronidase; Belongs to the glycosyl hydrolase 2 family.
 
     0.718
AEN96404.1
COG3345 Alpha-galactosidase.
       0.532
AEN96730.1
Hypothetical protein.
 
  
 0.507
AEN96405.1
Conserved hypothetical membrane spanning protein; COG2333 Predicted hydrolase (metallo-beta-lactamase superfamily).
       0.504
AEN96399.1
1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase; COG1691 NCAIR mutase (PurE)-related proteins.
       0.482
larC
Hypothetical protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family.
  
    0.415
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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