Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN96605.1COG1032 Fe-S oxidoreductase. (620 aa)    
Predicted Functional Partners:
AEN96606.1
Fe-S oxidoreductase; COG5011 Uncharacterized protein conserved in bacteria.
    0.987
AEN96607.1
COG1530 Ribonucleases G and E.
 
     0.864
hisI
COG0107 Imidazoleglycerol-phosphate synthase; In the C-terminal section; belongs to the PRA-PH family.
       0.754
AEN96604.1
Hypothetical protein.
       0.741
hisB
COG0131 Imidazoleglycerol-phosphate dehydratase.
       0.680
AEN96603.1
COG3274 Uncharacterized protein conserved in bacteria.
       0.651
AEN96608.1
Cellobiose phosphorylase-like protein; COG3459 Cellobiose phosphorylase.
       0.539
AEN96621.1
COG2868 Predicted ribosomal protein.
  
    0.533
AEN96609.1
Hypothetical protein.
       0.525
hisG
ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
  
    0.523
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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