Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AEN96655.1Aluminum resistance protein; COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance. (432 aa)    
Predicted Functional Partners:
miaA
tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
       0.816
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
       0.816
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
       0.736
AEN96660.1
COG2081 Predicted flavoproteins.
       0.728
AEN96659.1
COG2509 Uncharacterized FAD-dependent dehydrogenases.
       0.727
AEN98448.1
COG1982 Arginine/lysine/ornithine decarboxylases.
 
   
 0.711
AEN96652.1
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
       0.673
AEN96651.1
COG2891 Cell shape-determining protein.
       0.669
AEN96650.1
Peptidoglycan glycosyltransferase; COG0768 Cell division protein FtsI/penicillin-binding protein 2.
       0.667
AEN96653.1
Rod shape-determining protein MreB; COG1077 Actin-like ATPase involved in cell morphogenesis.
       0.666
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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