Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN96673.1Hypothetical protein; COG0457 FOG: TPR repeat. (393 aa)    
Predicted Functional Partners:
AEN96338.1
Hypothetical protein.
  
     0.756
AEN98280.1
Hypothetical protein; COG0457 FOG: TPR repeat.
  
     0.711
AEN95674.1
Cell wall hydrolase; COG3883 Uncharacterized protein conserved in bacteria.
  
     0.672
AEN97746.1
Hypothetical protein.
  
     0.662
AEN96476.1
Hypothetical protein.
  
     0.646
folD
Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
       0.625
AEN97591.1
Hypothetical protein.
  
     0.617
AEN95593.1
Hypothetical protein; COG2919 Septum formation initiator.
  
     0.610
AEN95281.1
COG4641 Uncharacterized protein conserved in bacteria.
  
     0.588
fhs
Formate--tetrahydrofolate ligase; COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family.
       0.585
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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