| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEN95240.1 | AEN96897.1 | RHOM_00565 | RHOM_08930 | DEAD/DEAH box helicase-like protein; COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. | NUDIX hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | 0.894 |
| AEN95240.1 | groL | RHOM_00565 | RHOM_09330 | DEAD/DEAH box helicase-like protein; COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.473 |
| AEN95240.1 | nnrE | RHOM_00565 | RHOM_07850 | DEAD/DEAH box helicase-like protein; COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. | YjeF-like protein/carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the r [...] | 0.934 |
| AEN95695.1 | nnrE | RHOM_02865 | RHOM_07850 | Hypothetical protein; COG0802 Predicted ATPase or kinase. | YjeF-like protein/carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the r [...] | 0.762 |
| AEN95770.1 | nnrE | RHOM_03240 | RHOM_07850 | Isochorismatase hydrolase; COG1335 Amidases related to nicotinamidase. | YjeF-like protein/carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the r [...] | 0.641 |
| AEN95921.1 | nnrE | RHOM_03995 | RHOM_07850 | Glycosyltransferase Family 35 candidate glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. | YjeF-like protein/carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the r [...] | 0.619 |
| AEN96680.1 | AEN96682.1 | RHOM_07835 | RHOM_07845 | Hypothetical protein. | Growth inhibitor; Toxic component of a type II toxin-antitoxin (TA) system. | 0.496 |
| AEN96680.1 | nnrE | RHOM_07835 | RHOM_07850 | Hypothetical protein. | YjeF-like protein/carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the r [...] | 0.650 |
| AEN96682.1 | AEN96680.1 | RHOM_07845 | RHOM_07835 | Growth inhibitor; Toxic component of a type II toxin-antitoxin (TA) system. | Hypothetical protein. | 0.496 |
| AEN96682.1 | nnrE | RHOM_07845 | RHOM_07850 | Growth inhibitor; Toxic component of a type II toxin-antitoxin (TA) system. | YjeF-like protein/carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the r [...] | 0.689 |
| AEN96682.1 | rex | RHOM_07845 | RHOM_07855 | Growth inhibitor; Toxic component of a type II toxin-antitoxin (TA) system. | Redox-sensing transcriptional repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. | 0.505 |
| AEN96897.1 | AEN95240.1 | RHOM_08930 | RHOM_00565 | NUDIX hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | DEAD/DEAH box helicase-like protein; COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. | 0.894 |
| AEN96897.1 | nnrE | RHOM_08930 | RHOM_07850 | NUDIX hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. | YjeF-like protein/carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the r [...] | 0.955 |
| AEN98254.1 | nnrE | RHOM_15740 | RHOM_07850 | Hypothetical protein; COG0655 Multimeric flavodoxin WrbA. | YjeF-like protein/carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the r [...] | 0.644 |
| groL | AEN95240.1 | RHOM_09330 | RHOM_00565 | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | DEAD/DEAH box helicase-like protein; COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. | 0.473 |
| groL | nnrE | RHOM_09330 | RHOM_07850 | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | YjeF-like protein/carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the r [...] | 0.820 |
| nnrE | AEN95240.1 | RHOM_07850 | RHOM_00565 | YjeF-like protein/carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the r [...] | DEAD/DEAH box helicase-like protein; COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. | 0.934 |
| nnrE | AEN95695.1 | RHOM_07850 | RHOM_02865 | YjeF-like protein/carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the r [...] | Hypothetical protein; COG0802 Predicted ATPase or kinase. | 0.762 |
| nnrE | AEN95770.1 | RHOM_07850 | RHOM_03240 | YjeF-like protein/carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the r [...] | Isochorismatase hydrolase; COG1335 Amidases related to nicotinamidase. | 0.641 |
| nnrE | AEN95921.1 | RHOM_07850 | RHOM_03995 | YjeF-like protein/carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the r [...] | Glycosyltransferase Family 35 candidate glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. | 0.619 |
