Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN96687.1Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. (220 aa)    
Predicted Functional Partners:
AEN96688.1
2-isopropylmalate synthase; COG0119 Isopropylmalate/homocitrate/citramalate synthases.
 
    0.784
AEN96686.1
COG0538 Isocitrate dehydrogenases; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
       0.619
AEN96685.1
ABC transporter; COG0488 ATPase components of ABC transporters with duplicated ATPase domains.
       0.614
AEN96065.1
Regulatory protein GntR HTH; COG2186 Transcriptional regulators.
 
  
 0.548
AEN96689.1
COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain.
       0.506
AEN95885.1
COG1414 Transcriptional regulator.
  
  
 0.450
rex
Redox-sensing transcriptional repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
       0.425
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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