Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN96698.1COG2190 Phosphotransferase system IIA components. (170 aa)    
Predicted Functional Partners:
AEN96697.1
PTS system, N-acetylglucosamine-specific IIBC component; COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.
 0.999
AEN96296.1
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.997
AEN96699.1
Transcriptional antiterminator, BglG; COG3711 Transcriptional antiterminator.
 
 
 
 0.963
AEN96403.1
Sugar transporter; COG2211 Na+/melibiose symporter and related transporters.
 
    
 0.870
AEN98306.1
PTS system, fructose-specific, IIABC component; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).
 
  
 0.777
AEN97937.1
Hypothetical protein; COG1073 Hydrolases of the alpha/beta superfamily.
    
 
 0.775
AEN95806.1
COG3711 Transcriptional antiterminator.
 
 
 0.706
AEN97393.1
Beta-galactosidase; COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; Belongs to the mannose-6-phosphate isomerase type 1 family.
 
  
 0.687
AEN97586.1
COG1925 Phosphotransferase system, HPr-related proteins.
 
 
 0.680
AEN96297.1
COG1925 Phosphotransferase system, HPr-related proteins.
 
 
 0.653
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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