STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN96748.1Glycoside hydrolase family 28; COG5434 Endopolygalacturonase; Belongs to the glycosyl hydrolase 28 family. (518 aa)    
Predicted Functional Partners:
AEN96747.1
Xylose isomerase domain-containing protein; COG1082 Sugar phosphate isomerases/epimerases.
 
     0.941
AEN96572.1
Glucosyl hydrolase family protein; COG4225 Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins.
   
 0.930
AEN96751.1
Glucosyl hydrolase family protein.
 
   
 0.875
AEN98064.1
Pectinesterase; COG4677 Pectin methylesterase.
 
   
 0.811
AEN96746.1
Hypothetical protein.
 
     0.789
AEN96752.1
Extracellular solute-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.
 
   
 0.753
kduI
5-keto-4-deoxyuronate isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.
 
   
 0.732
AEN96749.1
Binding-protein-dependent transporters inner membrane component; COG0395 ABC-type sugar transport system, permease component.
 
     0.672
AEN96750.1
Binding-protein-dependent transporters inner membrane component; COG1175 ABC-type sugar transport systems, permease components.
 
     0.614
AEN96048.1
Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
 
      0.523
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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