Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN96792.1N-acetylmannosamine kinase; COG1737 Transcriptional regulators. (310 aa)    
Predicted Functional Partners:
AEN96791.1
NAD(FAD)-utilizing dehydrogenase; COG2081 Predicted flavoproteins.
       0.844
cmk
COG0283 Cytidylate kinase.
       0.812
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
       0.771
AEN96788.1
4-hydroxy-3-methylbut-2-enyl diphosphate reductase/S1 RNA-binding domain protein; COG0539 Ribosomal protein S1.
       0.763
AEN96697.1
PTS system, N-acetylglucosamine-specific IIBC component; COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.
  
  
 0.688
AEN96787.1
MCP methyltransferase, CheR-type; COG1352 Methylase of chemotaxis methyl-accepting proteins.
     
 0.636
AEN98306.1
PTS system, fructose-specific, IIABC component; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).
     
 0.626
AEN97393.1
Beta-galactosidase; COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; Belongs to the mannose-6-phosphate isomerase type 1 family.
  
  
 0.546
AEN96793.1
Hypothetical protein; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
       0.517
AEN97743.1
Hypothetical protein; COG3935 Putative primosome component and related proteins.
  
     0.478
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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