STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN96825.1Hypothetical protein; COG0822 NifU homolog involved in Fe-S cluster formation. (230 aa)    
Predicted Functional Partners:
AEN96824.1
Hypothetical protein.
 
    0.962
AEN97149.1
Cysteine desulfurase, SufS subfamily protein; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
  
 
 0.950
iscS
Cysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
  
 0.896
AEN96144.1
Cysteine desulfurase NifS; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes.
  
 0.896
AEN96209.1
COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes.
  
 0.896
AEN97152.1
FeS assembly ATPase SufC; COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component.
  
  
 0.780
AEN97150.1
Hypothetical protein; COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component.
  
  
 0.659
AEN97151.1
COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component.
  
  
 0.659
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.606
AEN97429.1
COG0443 Molecular chaperone; Belongs to the heat shock protein 70 family.
  
 0.606
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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