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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN96905.1Putative metal-binding protein; COG2158 Uncharacterized protein containing a Zn-finger-like domain. (87 aa)    
Predicted Functional Partners:
AEN96906.1
Sirohydrochlorin cobaltochelatase; COG4822 Cobalamin biosynthesis protein CbiK, Co2+ chelatase.
       0.833
deoB
Hypothetical protein; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
       0.773
AEN96909.1
Periplasmic binding protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component.
 
     0.709
AEN96910.1
COG4822 Cobalamin biosynthesis protein CbiK, Co2+ chelatase.
 
     0.696
AEN96907.1
Ferric enterobactin transport ATP-binding protein fepC; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components.
 
     0.684
AEN96908.1
Transporter permease; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
     0.667
AEN96912.1
precorrin-6Y C(5,15)-methyltransferase; COG2099 Precorrin-6x reductase.
 
     0.639
AEN96902.1
Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family.
       0.497
prfC
Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
       0.497
AEN96917.1
precorrin-8X methylmutase CbiC/CobH; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase.
       0.410
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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