Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN96910.1COG4822 Cobalamin biosynthesis protein CbiK, Co2+ chelatase. (543 aa)    
Predicted Functional Partners:
AEN96912.1
precorrin-6Y C(5,15)-methyltransferase; COG2099 Precorrin-6x reductase.
 
  
 0.990
AEN96906.1
Sirohydrochlorin cobaltochelatase; COG4822 Cobalamin biosynthesis protein CbiK, Co2+ chelatase.
 
 
0.987
AEN96909.1
Periplasmic binding protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component.
 
     0.956
AEN96914.1
COG2073 Cobalamin biosynthesis protein CbiG.
 
  
 0.942
AEN96915.1
COG2875 Precorrin-4 methylase.
 
  
 0.927
AEN96908.1
Transporter permease; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
     0.912
cbiD
Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.902
AEN96913.1
Cobalt-precorrin-3b c(17)-methyltransferase; COG1010 Precorrin-3B methylase.
 
  
 0.895
cbiA
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
 
 0.884
AEN96907.1
Ferric enterobactin transport ATP-binding protein fepC; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components.
 
     0.875
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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