node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEN96906.1 | AEN96912.1 | RHOM_08975 | RHOM_09005 | Sirohydrochlorin cobaltochelatase; COG4822 Cobalamin biosynthesis protein CbiK, Co2+ chelatase. | precorrin-6Y C(5,15)-methyltransferase; COG2099 Precorrin-6x reductase. | 0.999 |
AEN96906.1 | AEN96913.1 | RHOM_08975 | RHOM_09010 | Sirohydrochlorin cobaltochelatase; COG4822 Cobalamin biosynthesis protein CbiK, Co2+ chelatase. | Cobalt-precorrin-3b c(17)-methyltransferase; COG1010 Precorrin-3B methylase. | 0.997 |
AEN96906.1 | AEN96915.1 | RHOM_08975 | RHOM_09020 | Sirohydrochlorin cobaltochelatase; COG4822 Cobalamin biosynthesis protein CbiK, Co2+ chelatase. | COG2875 Precorrin-4 methylase. | 0.999 |
AEN96906.1 | AEN96917.1 | RHOM_08975 | RHOM_09030 | Sirohydrochlorin cobaltochelatase; COG4822 Cobalamin biosynthesis protein CbiK, Co2+ chelatase. | precorrin-8X methylmutase CbiC/CobH; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | 0.995 |
AEN96906.1 | AEN96923.1 | RHOM_08975 | RHOM_09060 | Sirohydrochlorin cobaltochelatase; COG4822 Cobalamin biosynthesis protein CbiK, Co2+ chelatase. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.922 |
AEN96906.1 | cbiA | RHOM_08975 | RHOM_09000 | Sirohydrochlorin cobaltochelatase; COG4822 Cobalamin biosynthesis protein CbiK, Co2+ chelatase. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.970 |
AEN96906.1 | cbiD | RHOM_08975 | RHOM_09025 | Sirohydrochlorin cobaltochelatase; COG4822 Cobalamin biosynthesis protein CbiK, Co2+ chelatase. | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.995 |
AEN96906.1 | cobD | RHOM_08975 | RHOM_09035 | Sirohydrochlorin cobaltochelatase; COG4822 Cobalamin biosynthesis protein CbiK, Co2+ chelatase. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.919 |
AEN96906.1 | cobQ | RHOM_08975 | RHOM_09065 | Sirohydrochlorin cobaltochelatase; COG4822 Cobalamin biosynthesis protein CbiK, Co2+ chelatase. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.995 |
AEN96906.1 | cobS | RHOM_08975 | RHOM_09050 | Sirohydrochlorin cobaltochelatase; COG4822 Cobalamin biosynthesis protein CbiK, Co2+ chelatase. | Cobalamin 5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.962 |
AEN96912.1 | AEN96906.1 | RHOM_09005 | RHOM_08975 | precorrin-6Y C(5,15)-methyltransferase; COG2099 Precorrin-6x reductase. | Sirohydrochlorin cobaltochelatase; COG4822 Cobalamin biosynthesis protein CbiK, Co2+ chelatase. | 0.999 |
AEN96912.1 | AEN96913.1 | RHOM_09005 | RHOM_09010 | precorrin-6Y C(5,15)-methyltransferase; COG2099 Precorrin-6x reductase. | Cobalt-precorrin-3b c(17)-methyltransferase; COG1010 Precorrin-3B methylase. | 0.999 |
AEN96912.1 | AEN96915.1 | RHOM_09005 | RHOM_09020 | precorrin-6Y C(5,15)-methyltransferase; COG2099 Precorrin-6x reductase. | COG2875 Precorrin-4 methylase. | 0.999 |
AEN96912.1 | AEN96917.1 | RHOM_09005 | RHOM_09030 | precorrin-6Y C(5,15)-methyltransferase; COG2099 Precorrin-6x reductase. | precorrin-8X methylmutase CbiC/CobH; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | 0.999 |
AEN96912.1 | AEN96923.1 | RHOM_09005 | RHOM_09060 | precorrin-6Y C(5,15)-methyltransferase; COG2099 Precorrin-6x reductase. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.952 |
AEN96912.1 | cbiA | RHOM_09005 | RHOM_09000 | precorrin-6Y C(5,15)-methyltransferase; COG2099 Precorrin-6x reductase. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.989 |
AEN96912.1 | cbiD | RHOM_09005 | RHOM_09025 | precorrin-6Y C(5,15)-methyltransferase; COG2099 Precorrin-6x reductase. | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.999 |
AEN96912.1 | cobD | RHOM_09005 | RHOM_09035 | precorrin-6Y C(5,15)-methyltransferase; COG2099 Precorrin-6x reductase. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.980 |
AEN96912.1 | cobQ | RHOM_09005 | RHOM_09065 | precorrin-6Y C(5,15)-methyltransferase; COG2099 Precorrin-6x reductase. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.997 |
AEN96912.1 | cobS | RHOM_09005 | RHOM_09050 | precorrin-6Y C(5,15)-methyltransferase; COG2099 Precorrin-6x reductase. | Cobalamin 5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.990 |