Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN96988.1Hypothetical protein; COG0086 DNA-directed RNA polymerase, beta' subunit/160 kD subunit. (367 aa)    
Predicted Functional Partners:
AEN96987.1
COG3864 Uncharacterized protein conserved in bacteria.
 
     0.907
AEN96304.1
Hypothetical protein; COG0714 MoxR-like ATPases.
 
    0.790
AEN95698.1
Hypothetical protein.
  
     0.626
AEN96989.1
gamma-D-glutamyl-{L}-meso-diaminopimelate peptidase I, metallo peptidase, MEROPS family M14C; COG3409 Putative peptidoglycan-binding domain-containing protein.
       0.605
AEN97985.1
Hypothetical protein.
  
     0.603
AEN97968.1
Hypothetical protein; COG1388 FOG: LysM repeat.
 
  
 0.526
AEN95945.1
Hypothetical protein.
  
   0.515
AEN96087.1
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.
    
 
 0.478
AEN97230.1
COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
 
     0.476
AEN96991.1
NADPH-dependent glutamate synthase GltA2; COG1145 Ferredoxin.
   
   0.430
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
Server load: low (26%) [HD]