Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN96991.1NADPH-dependent glutamate synthase GltA2; COG1145 Ferredoxin. (903 aa)    
Predicted Functional Partners:
AEN97041.1
COG0067 Glutamate synthase domain 1.
 
 
 0.999
AEN96087.1
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.
  
 
 0.980
AEN95678.1
COG2086 Electron transfer flavoprotein, beta subunit.
  
 
 0.974
AEN97011.1
COG2086 Electron transfer flavoprotein, beta subunit.
  
 
 0.974
AEN97017.1
COG2086 Electron transfer flavoprotein, beta subunit.
  
 
 0.974
hypA
Hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.972
AEN96981.1
COG1142 Fe-S-cluster-containing hydrogenase components 2.
   
 
 0.952
AEN95190.1
COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.
  
 
 0.950
AEN97047.1
Transcriptional regulator; COG4624 Iron only hydrogenase large subunit, C-terminal domain.
   
 
 0.950
AEN97434.1
Putative iron-sulfur-binding membrane protein; COG0348 Polyferredoxin.
  
 
 0.946
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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